Eficácia:

Literatura Científica
- Alexandrita
- Yag


Confirme você mesmo a eficácia desta tecnologia nas publicações médicas internacionais que podem ser pesquisadas no site oficial do Ministério da Saúde www.bireme.br da seguinte maneira: selecionar • literatura científica, depois MEDLINE 1996_2006 e depois pesquisar as palavras chaves:
“Dynamic Cooling Device” Você encontrará entre outros, um trabalho publicado por médicos do Dept de Dermato da Boston Universtiy of Medicine publicado na revista Lasers Surg Méd 31(4) 247-51, 2002, que demonstra a necessidade de jogar no mínimo 20 milisegundos de spray.
“Alexandrite hair removal” (Se for aplicado o Gentlelase que é laser emitido por cristal de Alexandrita). “Yag hair removal” (se for aplicado o Gentleyag Yag). Ambos são laser de luz infravermelha associados ao gás congelante protetor anestésico (DCD).

É bom lembrar que estes foram resultados obtidos em pesquisa em indivíduos de pele muito branca, diferente da pele do brasileiro, onde o resultado pode ser inferior. Por outro lado muitas destas pesquisas foram realizadas com os referidos lasers sem os também abaixo comprovados benefícios do pré congelamento da pele.

Literatura do Gentlelase (para pele clara - Alexandrita):
Nahm e colaboradores, Universidade de Boston. País da publicação USA em 2002: O laser de alexandrita tem sido eficaz na remoção de pêlos. O gás congelante protetor (DCD) minimiza o dano epidérmico. Jatos tão curtos quanto 20 milissegundos, foram benéficos para a redução da dor.

Galadari, Emirados Árabes.País da publicação USA em janeiro de 2003: O laser permite tratamento de pêlos indesejáveis com menos desconforto que outros métodos de epilação (epilação é o termo técnico para depilação definitiva).

Moreno. Universidade de Barcelona. País da publicação USA em abril 2004: Laser de alexandrita pode induzir a uma supressão reversível de melanócitos causando hipopigmentação (manchas claras) de longa duração.

Weisberg. Centro de Pele e Laser da Pensilvânia. País da publicação USA em abril de 2003: O laser de alexandrita é eficaz e seguro na remoção de pêlos em diferentes tipos de pele. O grau de complicações vai aumentando quando aumenta a pigmentação da pele e a potência do laser.

Hussain Nova York e Nova Jersey. País da publicação USA em março de 2003: Resultados de 9 meses após 1 aplicação 32% de redução

Após 2 aplicações 44% de redução
Após 3 aplicações 55% de redução

Sanchez e colaboradores. Universidade do Alabama. País da publicação USA em março de 2002: Enquanto estudos maiores, controlados, cegos e uniformes ainda são necessários, a remoção de pêlos a laser parece ser um adjuvante útil no tratamento de pacientes com hirsurtismo (pêlos anormais em mulheres).

Liew. Hospital Mount Vernon, Reino Unido. País da publicação USA em 2002: Um clareamento de 30 a 50% dos pêlos tem sido geralmente reportado 6 meses após o último tratamento. Métodos para reduzir a incidência de efeitos adversos incluem clareamento da pele, evitar o sol antes do tratamento a laser e congelamento da pele durante o tratamento.

Eremia e colaboradores. Universidade da Califórnia - USA. País da publicação USA em novembro de 2001: Após quatro tratamentos com o laser de alexandrita com altas energias, houve uma redução média de 90% dos pêlos. Ambos os lasers de alexandrita e diodo (Light Sheer) produziram exelente redução de pêlos em longo prazo. O resultado com o laser de alexandita foi melhor.

Eremia e colaboradores. Universidade da Califórnia - USA. País da publicação USA em novembro de 2001: A após 3 tratamentos os pacientes tiveram uma redução de 74% com o Laser de Alexandrita com gás congelante protetor.

Lu e colaboradores. Hospital geral de Cathay. Taiwan. País da publicação USA em outubro de 2001: Após 2 tratamentos o grau de clareamento nas axilas e pernas foram 61% e 62% respectivamente. Após 5 tratamentos houve uma média de clareamento de 91% na axila, 86% nas pernas e a média de clareamento se manteve após um acompanhamento longo.

Handrick e Alster. Universidade de Georgetown, Washington, DC. País da publicação USA em julho de 2001: Na comparação do laser de Alexandrita e o laser de Diodo os efeitos colaterais incluíram raramente dor e bolha foram raras com ambos os lasers, mas foram encontrados com mais freqüência com o laser de Diodo(Light Sheer).

Freedman e Earley Universidade de Georgetown, Washington, DC . País da publicação USA em Setembro de 2001: Enfermeiras treinadas e médicos obtiveram resultados finais semelhantes na operação de equipamentos de laser para redução de pêlos.

Laughlin e Dudley. Universidade de Ottawa, Ontário. País da publicação Canadá em abril de 2000: A média de perda de cabelo após o primeiro tratamento foi 43% com o laser de Alexandritra de 3ms(igual ao Gentle Laser), com 60% das regiões mostrando uma perda de cabelo acima de 30%.

Dierickx. Escola de Medicina de Harvard, USA. País da publicação USA em dezembro de 2000: Laser para remoção de pêlos oferece o potencial para o tratamento de redução de pelos duradouros em grandes áreas.

Raulin e colaboradores. Laserklinik Karlsruhe, Alemanha. País da publicação USA em 2000: Tecnologia analgésica por resfriamento está firmemente estabelecida na terapia dermatológica com laser.

Eremia e Newman. Universidade da Califórnia de Los Angeles - USA. País da publicação USA em julho de 2000: O laser Diodo(Light Sheer) causa mais desconforto que o Laser de Alexandrita para redução definitiva de pêlos.

Lloud e Mirkov. Universidade de Ohio USA. País da publicação USA em julho de 2000: Na região do biquíni, após 5 tratamentos, os pacientes tiveram um clareamento médio de 78% dos seus cabelos sem cicatrizes ou alterações pigmentares. Estes resultados foram observados 1 ano após o tratamento.

Ono e Tateshita. Universidade de Fukushima, Japão. País da publicação França em julho de 2000: A epiderme foi completamente protegida pelo gás congelante protetor do Laser de Alexandrita.

Garcia e colaboradores. Universidade do King Abdulaziz, Arábia Saudita. País da publicação USA em fevereiro de 2000: O laser de Alexandrita é seguro para remoção de pêlos em pessoas de peles mais escuras.

Görgü e colaboradores. Centro de Laser de Ancara, Turkia. País da publicação USA em janeiro de 2000: A média do clareamento com laser de Alexandrita após 3 aplicações foi de 74%.

Goldberg e Ahkami. Escola de Medicina de Nova Jérsei. País da publicação USA em 1999: A porcentagem média de redução de pêlos após 3 tratamentos com laser de Alexandrita foi de 33%.

McDaniel e colaboradores. Centro de Laser da Virgínia - USA. País da publicação USA em junho de 1999: A redução máxima de pêlos observada foi 40% para lábios (bigode), 56% para perna, 50% no dorso e 15% na área do biquíni. A redução de cabelos nos lábios aumentou entre 40 a 54% quando feita uma segunda aplicação. A conclusão é que o Laser de Alexandrita é seguro e eficaz na redução do crescimento de pêlos. A eficácia varia com a localização anatômica.

Nanni e Alster. Instituto de Laser de Washington - USA. País da publicação USA em agosto de 1999: Os efeitos colaterais com Laser de Alexandrita e outros foram dor, eritema, edema, hipo e hiperpigmentação, bolhas, crostas, erosões, púrpura e foliculites. A remoção de pelos com laser é um procedimento seguro quando as características dos pacientes como tipo de pele, localização anatômica, e bronzeamentos da pele são considerados na seleção dos parâmetros do tratamento com o laser. Não ocorreram complicações persistentes como infecções ou cicatrizes em longo prazo.

Nanni e Alster. Instituto de Laser de Washington - USA. País da publicação USA em 1999: A contagem de cabelos após tratamento com laser de Alexandrita foi reduzida para 66% com 1 mês de tratamento, 27% com 3 meses e 4% com 6 meses.

Ash e colaboradores. Hospital Naval de Okinawa, Japão. País da publicação USA em abril de 1999: O uso de laser para depilação de pêlos tornou-se recentemente uma modalidade comum para médicos. O grau e a duração da redução varia com a região anatômica e melhora após múltiplos tratamentos.

Boss e colaboradores. Universidade da Nova Jérsei. País da publicação USA em abril de 1999: Os pacientes reportaram 60 a 80% de redução de pêlos em 6 meses de tratamento.

Lask e colaboradores. Universidade da Califórnia de Los Angeles - USA. País da publicação USA em janeiro de 1999: Os sistemas de laser e luz intensa são eficientes e seguros. Múltiplos tratamentos são necessários devido a natureza do ciclo de crescimento do cabelo.

Rogers e Colaboradores. Universidade de Saint Louis - USA. País da publicação USA em novembro de 1999: A percentagem de redução de pêlos observada 2 meses após 1 aplicação de laser de Alexandrita foi de 55%, e 3 meses após a área tratada mostrou 27% de redução


Literatura do Gentleyag (para barba e pele morena):

Base de dados : MEDLINE_1996-2006
Pesquisa : yag AND hair AND removal


Autor: Rao J; Goldman MP
Endereço: Dermatology/Cosmetic Laser Associates of La Jolla, Inc., California 92037, USA.
Título: Prospective, comparative evaluation of three laser systems used individually and in combination for axillary hair removal.
Source: Dermatol Surg;31(12):1671-6; discussion 1677, 2005 Dec.
País de publicação: United States
Resumo: BACKGROUND: Using the concept of selective photothermolysis, a variety of laser systems have been developed to remove unwanted hair. OBJECTIVE: To evaluate the relative efficacy, tolerability, and subject satisfaction of three different laser systems used individually and in rotation for axillary hair removal. METHODS: Twenty female patients (17 with dark-colored hair, 3 with red or light-colored hair) with Fitzpatrick phototype II skin received three treatments performed at 6- to 8-week intervals. Each axilla was divided in half to yield four distinct areas that were treated by the following lasers: (1) three sessions with a long-pulse 755 nm alexandrite laser, (2) three sessions with a long-pulse 810 nm diode laser, (3) three sessions with a long-pulse 1,064 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser, and (4) rotational treatment consisting of a single session by each of the three laser systems. Percent hair reduction and acute and long-term side effects were evaluated after treatment. Subjects completed questionnaires assessing tolerability and satisfaction.
RESULTS: All subjects tolerated the treatments well, with only local, transient side effects seen. At the 3-month follow-up, the greatest average hair reduction was comparably similarly seen after the alexandrite laser at 59.3 +/- 9.7% and the 810 nm diode laser at 58.7 +/- 7.7%. The Nd:YAG laser and rotational regimens were less efficacious, with 31.9 +/- 11.1% and 39.8 +/- 10.1% hair reduction, respectively. Subjects with red or light-colored hair experienced 5 to 15% reduced efficacy with any laser system used. Subjects found the alexandrite and diode lasers to be equally tolerable, with only slight discomfort, and the Nd:YAG laser to be the least comfortable of the three systems. Overall, subject satisfaction of each treated site, in decreasing order, was (1) the 810 nm diode laser, (2) the alexandrite laser, (3) rotational therapy, and (4) the Nd:YAG laser. CONCLUSION: At the 3-month follow-up, the long-pulse alexandrite and 810 nm diode lasers demonstrated no statistically significant differences in efficacy, comparable efficacy and tolerability, and highest subject satisfaction. Rotational therapy with the three laser systems is not as effective as treatment with the alexandrite laser or diode laser alone but is statistically more effective than use of the long-pulse Nd:YAG system alone. Individuals with red or light-colored hair and Fitzpatrick phototype II skin have decreased efficacy of laser treatment than those with dark-colored hair and the same phototype.


Autor: Wanner M
Endereço: Department of Dermatology, College of Physicians and Surgeons, Columbia University, 161 Fort Washington, New York, NY 10032, USA. maw44@columbia.edu
Título: Laser hair removal.
Source: Dermatol Ther;18(3):209-16, 2005 May-Jun.
País de publicação: Denmark
Resumo: Since 1996, there have been numerous advances in hair laser removal that utilize melanin as a chromophore. All of the devices on the market may be used in patients with light skin (phototypes I-III) and yield hair reduction near 75%. The ruby (694 nm) laser, alexandrite (755 nm) laser, and diode (810 nm) laser, as well as intense pulsed light are commonly used devices for hair laser removal. The long-pulsed Nd:YAG (1064 nm) laser represents the safest device for hair removal in dark-skinned patients because of its long wavelength, although the diode laser, alexandrite laser, and intense pulse light may be used. For treatment of light hair, combination radiofrequency and optical devices as well as photodynamic therapy are under investigation.


Autor: Guardiano RA; Norwood CW
Endereço: Department of Dermatology, National Naval Medical Center, Bethesda, Maryland 20889, USA. raguardiano@bethesda.med.navy.mil Título: Direct comparison of EMLA versus lidocaine for pain control in Nd:YAG 1,064 nm laser hair removal.
Source: Dermatol Surg;31(4):396-8, 2005 Apr.
País de publicação: United States
Resumo: BACKGROUND: Laser hair removal is an effective therapy for the treatment of hirsutism, hypertrichosis, and pseudofolliculitis barbae. Although side effects are uncommon, pain is described by most patients undergoing long-pulsed neodymium:yttrium-aluminum-garnet (Nd:YAG) 1,064 nm laser therapy. OBJECTIVES: To compare the efficacy of topical eutectic mixture of local anesthetics (EMLA) versus topical lidocaine (LMX) in pain control for Nd:YAG 1,064 nm laser hair removal. METHODS: Sixty-four patients were enrolled in a double-blind randomized study over a 6-month period. Each patient had half of the treatment area covered with EMLA and the other half with LMX 30 minutes prior to treatment. Neither was applied under occlusion. Immediately following their treatment session, patients completed a visual analog pain scale. RESULTS: There was no statistically significant difference in pain control between EMLA and LMX. However, female test subjects demonstrated lower pain scores than male test subjects. CONCLUSIONS: Nd:YAG 1,064 nm laser hair removal is a painful procedure. Topical anesthetics have been proven to reduce pain for laser hair removal. There is no statistically significant difference between the two most commonly used topical anesthetics for pain control in laser hair removal. Therefore, cost and minimizing potential side effects should guide the physician in selecting the appropriate anesthetic.
NOSSO COMENTÁRIO: O objetivo do trabalho era avaliar duas pomadas
Anestésicas. Além das pomadas o gás é mais um método de anestesia.


Autor: Ferraro GA; Perrotta A; Rossano F; D'Andrea F
Endereço: Centro Direzionale di Napoli, Italia. gaferraro@libero.it
Título: Neodymium: yttrium-aluminum-garnet long impulse laser for the elimination of superfluous hair: experiences and considerations from 3 years of activity.
Source: Aesthetic Plast Surg;28(6):431-4, 2004 Nov-Dec.
País de publicação: United States
Resumo: This study examined the results obtained with a modern apparatus for laser hair removal (neodymium: yttrium-aluminum-garnet [Nd:YAG] laser at long impulses with a wave-length of 1,064 nm; Q-switched laser) over a follow-up period of 3 years. A large heterogeneous group of 480 patients was taken into consideration. These patients were treated according to a standard protocol with monthly checkups and a personalized protocol at deferred appointments. The results, discovered by means of the most objective procedure possible, were retrieved and put into a graph showing two different curves for the repopulation of hair. In their clinical travels, the authors observed an average variable regrowth of 40% to 65%, allowing them to affirm that laser hair removal using Nd:YAG at long impulses is decisively efficient in obtaining long-term results. The use of a protocol (denominated [quot ]prolonged monthly checkup[quot ]) with laser sessions at ever-decreasing periods permits, among other things, more outstanding and advantageous results for the patient. Thanks to more efficiently synchronized phases of the biologic hair cycle, this shortens and moves the telegenic phases closer and also renders the anagenic phases (those in which the selective photoermolysis on the pilipheric follicle proves to be efficient) more efficient. Personalization of the treatment relative to the monthly health checkup sessions is of fundamental importance to the scope of obtaining the best results in terms of cost-benefit rate, provided submassimal fluxes are (i.e., those well-tolerated by the patient) used. All this allows hair removal that is not definitive, but which becomes progressively permanent (i.e., characterized by ever-growing periods of lack of hair sustained by sporadic maintenance laser sessions based on the individual's necessity).


Autor: Parlette EC; Kroeger N; Ross EV
Endereço: LT MC USNR, Third Year Resident, Naval Medical Center, San Diego, California 92134-5000, USA. ecparlette@hotmail.com
Título: Nd:YAG laser treatment of recalcitrant folliculitis decalvans.
Source: Dermatol Surg;30(8):1152-4, 2004 Aug.
País de publicação: United States
Resumo: BACKGROUND: The scarring follicular disorders pose challenging therapeutic dilemmas. OBJECTIVE: Hair removal lasers have recently been shown to be efficacious in the management of these disorders. METHODS: We present a young, Fitzpatrick skin type VI African-American patient with recalcitrant folliculitis decalvans, whom we treated with the neodymium:yttrium aluminum garnet (Nd:YAG) laser. RESULTS: A remission of folliculitis decalvans was successfully achieved using the Nd:YAG for laser depilation.
CONCLUSION: Based on the optical properties of light in skin, the Nd:YAG laser is the best for laser depilation in dark individuals.


Autor: Battle EF; Hobbs LM
Endereço: Department of Dermatology, Howard University College of Medicine, 2041 Georgia Avenue NW, Washington, DC 20060, USA. drbattle@culturamed.com
Título: Laser-assisted hair removal for darker skin types.
Source: Dermatol Ther;17(2):177-83, 2004.
País de publicação: Denmark
Resumo: Before the advent of longer wavelengths, longer pulse durations and more efficient cooling devices, laser-assisted hair removal was best suited for phototypes I-III with dark terminal hairs. Now, laser-assisted hair removal can be performed safely and efficaciously on darker skin types.
The long-pulsed diode and Nd:YAG-wavelength-based laser systems are best suited to safely and effectively treat patients with darker skin types. By using conservative fluences, longer pulse durations and multiple treatments, safe and effective laser-assisted hair removal is possible for darker skin types. Patients with darker skin who suffer from hirsutism, hypertrichosis, and pseudofolliculitis barbae can finally be treated safely and effectively.


Autor: Bouzari N; Tabatabai H; Abbasi Z; Firooz A; Dowlati Y
Endereço: Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
Título: Laser hair removal: comparison of long-pulsed Nd:YAG, long-pulsed alexandrite, and long-pulsed diode lasers.
Source: Dermatol Surg;30(4 Pt 1):498-502, 2004 Apr.
País de publicação: United States
Resumo: BACKGROUND: Advances in laser technology over the past several years have led to the development of numerous lasers for the treatment of unwanted hair. Laser wavelength is a key factor influencing treatment efficacy and complication rates. OBJECTIVE: To compare the efficacy and safety of laser hair removal using three different laser systems. METHODS: A retrospective study of 805 consecutive laser-assisted hair removal treatments, conducted on 75 patients by means of either a long-pulsed Nd:YAG, a long-pulsed alexandrite, or a long-pulsed diode laser is reported. All patients were evaluated at least 3 months after the last treatment, and their present conditions were compared with the 1st-day photographs. RESULTS: The mean hair reduction was 42.4%, 65.6%, and 46.9% in Nd:YAG, alexandrite, and diode lasers, respectively. When the number of treatment sessions was taken into account, the efficacy of alexandrite and diode lasers was not significantly different, whereas both systems were more efficacious than Nd:YAG. Neither of the laser systems showed better results for a particular skin type. The occurrence of side effects was not significantly different between three laser systems. CONCLUSION: Both long-pulsed alexandrite and long-pulsed diode laser systems are effective in the treatment of unwanted hair, and they are more efficacious than Nd:YAG laser.


Autor: Raff K; Landthaler M; Hohenleutner U
Endereço: Department of Dermatology, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany. kerstin.raff@klinik.uni-regensburg.de
Título: Optimizing treatment parameters for hair removal using long-pulsed Nd:YAG-lasers.
Source: Lasers Med Sci;18(4):219-22, 2004.
País de publicação: England
Resumo: Our aim was to determine the most effective treatment parameters for laser-assisted hair removal using long-pulsed Nd:YAG-lasers. 42 volunteers were treated with 1064 nm long-pulsed Nd:YAG-lasers. We used two different laser systems (Lyra XP, Wavelight and Smartepil II Deka-LMS) with various pulse lengths, fluences, and spot sizes. For each parameter, five test areas were treated one to five times at 4-week intervals. Follow-ups were performed 1, 3, 6, and 12 months after the last treatment. Percentual hair loss, side effects, and pain during treatment were evaluated. The average hair reduction 12 months after the last treatment using the Lyra XP was 48%, using the Smartepil II it ranged between 30% and 35%. There were no permanent side effects. Long-pulsed 1064 nm Nd:YAG-lasers are safe and effective for hair reduction. Although the different treatment parameters did not lead to a lot of differing hair reduction 12 months after the last treatment, the laser with the largest spot size and the longest pulse time showed the best results.


Autor: Tanzi EL; Alster TS
Endereço: Washington Institute of Dermatologic Laser Surgery, Washington, DC, USA.
Título: Long-pulsed 1064-nm Nd:YAG laser-assisted hair removal in all skin types.
Source: Dermatol Surg;30(1):13-7, 2004 Jan.
País de publicação: United States
Resumo: BACKGROUND: Although there are several different laser systems available for the reduction of unwanted hair, no single system has been shown to be superior in providing safe and effective hair removal in every skin type. The purpose of this study was to evaluate the safety and efficacy of a high-energy, long-pulsed, 1064-nm Nd:YAG laser with a contact cooling device for hair removal in skin phototypes I-VI. METHODS: Thirty-six adult patients (skin phototypes I-VI) with dark terminal facial or nonfacial hair were treated with a long-pulsed Nd:YAG laser (1064 nm, 10-mm spot size, fluence of 30 to 60 J/cm2). The selected pulse duration was dependent on the skin type of the patient: Skin types I/II, III/IV, and V/VI received 10, 20, and 30 ms, respectively. Three consecutive laser treatments were delivered to 36 skin sites at 4- to 6-week intervals. Hair counts and photographic evaluations of skin sites were obtained at baseline, immediately before each treatment session, and at 1, 3, and 6 months after the final laser treatment. RESULTS: Peak hair reduction was observed 1 month after the series of laser treatments with a mean hair reduction ranging from 58% to 62% on facial sites and 66% to 69% on nonfacial sites. At 6 months after a series of three long-pulsed Nd:YAG laser treatments, a mean hair reduction of 41% to 46% on the face and 48% to 53% on the body was found depending on the skin phototype. Adverse reactions included mild to moderate treatment pain, short-term erythema, and rare occurrences of transient pigmentary alteration without scarring. CONCLUSION: The long-pulsed 1064-nm Nd:YAG laser with contact cooling is a safe and effective method of hair reduction in patients of all skin types. Side effects were limited and transient.


Autor: Goh CL
Endereço: Dermatological and Laser Surgery Unit, National Skin Centre, 1 Mandalay Road, Singapore 305205.
clgoh@nsc.gov.sg
Título: Comparative study on a single treatment response to long pulse Nd:YAG lasers and intense pulse light therapy for hair removal on skin type IV to VI--is longer wavelengths lasers preferred over shorter wavelengths lights for assisted hair removal.
Source: J Dermatolog Treat;14(4):243-7, 2003 Dec.
País de publicação: England
Idioma: eng
Resumo: OBJECTIVE: To investigate the safety and effectiveness of a long pulsed Nd:YAG (1064nm) laser compared to a shorter wavelength intense pulse light system for assisted hair removal in volunteers with skin type 1V, V and VI. METHODS: Eleven patients of Fitzpatrick skin type IV-VI were recruited into the study. The area treated included the face (upper lips, chin and jaw area), axillae and legs. One half of the body was treated with the long pulse Nd:YAG laser and the other half was treated with the IPL system randomly under topical anesthesia. Degree of pain experienced during treatment, the treatment outcome and any complications were observed. Patients were reviewed at 2 weeks and 6 weeks post-treatment. RESULTS: Volunteers generally described pain from the IPL system as [quot ]prolonged burning sensation[quot ] but tolerable. Pain from Nd:YAG laser treatment was described as [quot ]pinprick[quot ] and more intense but tolerable. [quot ]Slowing of hair growth[quot ]was reported with IPL and Nd:YAG, but with a greater effect from Nd:YAG. Sixty-four percent and 73%(8/11) noticed hair reduction <20% after 6 weeks on IPL and Nd:YAG treated side respectively (ns). Post-inflammatory pigmentation occurred in some volunteers on the IPL treated sides whereas this was not seen on any Nd:YAG treated side, and three of these patients experienced blistering, followed by post-inflammatory pigmentation.
CONCLUSION: In our experience the long pulse width 1064 nm Nd:YAG laser, which can penetrate 5-7 mm into the dermis depths to reach the whole length of the hair follicle, would be expected to produce sufficient follicular injury with less epidermal damage in patients with darker skin type compared to shorter wavelength laser and light system.


Autor: Galadari I
Endereço: Faculty of Medicine and Health Sciences, Dubai, United Arab Emirates. galadari@email.com
Título: Comparative evaluation of different hair removal lasers in skin types IV, V, and VI.
Source: Int J Dermatol;42(1):68-70, 2003 Jan.
País de publicação: United States
Resumo: OBJECTIVES: We aimed to compare the results of treatment of skin types IV, V, and VI using three different laser systems. METHODS: One hundred female patients were compared using different laser systems: 35 patients underwent epilation using a Nd-Yag laser, 33 patients using an Alexandrite laser, and 32 patients using a Diode laser. RESULTS: Follow up 12 months after the multiple treatments (three to six sessions) showed an insignificant difference between these three groups (35-40%). CONCLUSION: Our findings indicate that all three laser systems tested can be used for dark skin; however, one should select a system that minimizes side-effects, primarily hypo- and hyper-pigmentation, especially when used for skin types IV, V, and VI.


Autor: Rogachefsky AS; Becker K; Weiss G; Goldberg DJ
Endereço: Skin Laser & Surgery Specialists of New York and New Jersey, Hackensack, NJ, USA.
Título: Evaluation of a long-pulsed Nd:YAG laser at different parameters: an analysis of both fluence and pulse duration.
Source: Dermatol Surg;28(10):932-5; discussion 936, 2002 Oct.
País de publicação: United States
Resumo: BACKGROUND: Effective hair removal continues to pose a challenge to the physician. The use of lasers represents a significant advance in epilation, but still requires further refinement. The long-pulsed Nd:YAG laser may offer advantages over other systems because of its significant depth of penetration and minimal absorption by epidermal melanin, but ideal parameters need to be determined. OBJECTIVE: To evaluate the efficacy of a long-pulsed Nd:YAG laser system and determine the optimal parameters for hair removal. METHODS: Twenty-two subjects were treated with a cryogen spray-cooled long-pulsed Nd:YAG laser. Four adjacent sites were assigned to each subject, where the following sets of parameters were utilized: 50 J/cm2 with a 25-msec pulse duration, 60 J/cm2 with a 50-msec pulse duration, 80 J/cm2 with a 50-msec pulse duration, and control. Hair counts were obtained immediately, 1 week, 1 month, and 3 months after treatment, and multivariate regression analysis was used to determine the significance of hair reduction. Acute reactions and adverse events were also evaluated. RESULTS: Treatment at all three sets of parameters resulted in significant mean hair reductions immediately, at 1 week, and at 1 month (P <.001). At 3 months, the higher settings of 60 J/cm2 and 50 msec and 80 J/cm2 and 50 msec were statistically significant for reduced mean hair counts (P =.014, P =.042, respectively), while the lowest setting at 50 J/cm2 and 25 msec was not significant (P =.079). Patient and physician assessments suggested optimal hair reduction at the highest fluence (80 J/cm2) and longest pulse duration (50 msec). The most common acute reactions were pain during treatment, erythema, and perifollicular edema, all of which were more severe with higher fluences.
CONCLUSION: The long-pulsed Nd:YAG laser is a safe and effective method of hair removal. Increased fluence (60-80 J/cm2) and longer pulse duration (50 msec) settings were generally correlated with reduced hair counts and improved clinical outcome.
NOSSO COMENTÁRIO: O autor usou laser com o gás congelante (criogeno)


Autor: Sanchez LA; Perez M; Azziz R
Endereço: Department of Obstetrics and Gynecology, The University of Alabama at Birmingham, 35233-7333, USA.
Título: Laser hair reduction in the hirsute patient: a critical assessment.
Source: Hum Reprod Update;8(2):169-81, 2002 Mar-Apr. ISSN: 1355-4786
País de publicação: England
Resumo: Hirsutism affects 5-10% of unselected women, depending on ethnicity and definition. The past two decades have seen the development of lasers for the removal of unwanted hair, using selective destruction of the hair follicle without damage to adjacent tissues. Selective photothermolysis relies on the absorption of a brief radiation pulse by specific pigmented targets, which generates and confines the heat to that selected target. In general, laser hair removal is most successful in patients with lighter skin colours and dark coloured hairs. Some studies have documented the results of laser hair removal in a controlled setting, although few have extended their observations beyond 1 year. In general, treatment with the ruby, alexandrite or diode lasers, or the use of intense pulsed light results in similar success rates, although these are somewhat lower for the neodymium:Yttrium-Aluminum-Garnet (nd:YAG) laser. Overall, laser hair removal should not be considered 'permanent', at least when considering the current data available. Repeated therapies are necessary, although complete alopoecia is rarely achieved and it is unclear at what point the maximum benefit is achieved from multiple therapies. While larger prospective, controlled, blinded and uniform studies are still needed, laser hair removal appears to be a useful adjuvant in the treatment of the hirsute patient.
Nosso comentário: O autor demonstra não ter experiência com laser, pois não viu pacientes com mais de um ano de evolução.


Autor: Liew SH
Endereço: Institute of Plastic Surgery, Mount Vernon Hospital, Northwood, Middlesex, UK. sehwangliew@hotmail.com
Título: Laser hair removal: guidelines for management.
Source: Am J Clin Dermatol;3(2):107-15, 2002.
País de publicação: New Zealand
Resumo: Laser-assisted hair removal is the most efficient method of long-term hair removal currently available. Several hair removal systems have been shown to be effective in this setting: ruby laser (694nm), alexandrite laser (755nm), diode laser (800nm), intense pulsed light source (590 to 1200nm) and the neodymium:yttrium-aluminium-garnet (Nd:YAG) laser (1064nm), with or without the application of carbon suspension. The parameters used with each laser system vary considerably. All these lasers work on the principle of selective photothermolysis, with the melanin in the hair follicles as the chromophobe. Regardless of the type of laser used multiple treatments are necessary to achieve satisfactory results. Hair clearance, after repeated treatments, of 30 to 50% is generally reported 6 months after the last treatment. Patients with dark colored skin (Fitzpatrick IV and V) can be treated effectively with comparable morbidity to those with lighter colored skin. Although there is no obvious advantage of one laser system over another in terms of treatment outcome (except the Nd:YAG laser, which is found to be less efficacious, but more suited to patients with darker colored skin), laser parameters may be important when choosing the ideal laser for a patient.
- Adverse effects reported after laser-assisted hair removal include erythema and perifollicular edema, which are common, and crusting and vesiculation of treatment site, hypopigmentation and hyperpigmentation (depending on skin color and other factors).
- Most complications are generally temporary.

- The occurrence of hypopigmentation after laser irradiation is thought to be related to the suppression of melanogenesis in the epidermis (which is reversible), rather than the destruction of melanocytes.
- Methods to reduce the incidence of adverse effects include lightening of the skin and sun avoidance prior to laser treatment, cooling of the skin during treatment, and sun avoidance and protection after treatment.

Proper patient selection and tailoring of the fluence used to the patient's skin type remain the most important factors in efficacious and well tolerated laser treatment. While it is generally believed that hair follicles are more responsive to treatment while they are in the growing (anagen) phase, conflicting results have also been reported. There is also no consensus on the most favorable treatment sites.


Autor: Lorenz S; Brunnberg S; Landthaler M; Hohenleutner U
Endereço: Department for Dermatology, University of Regensburg, 93053 Regensburg, Germany.
Lorenz@rkdernw1.ngate.uni-regensburg.de
Título: Hair removal with the long pulsed Nd:YAG laser: a prospective study with one year follow-up.
Source: Lasers Surg Med;30(2):127-34, 2002.
País de publicação: United States
Resumo: BACKGROUND AND OBJECTIVE: The aim was to investigate the efficacy, side effects, and the long-term results of a long pulsed Nd:YAG-Laser for hair removal in different hair colors and skin types. STUDY DESIGN/MATERIALS AND METHODS: We performed a prospective clinical study with 29 volunteers. Treatment was performed on the lower leg with a long pulsed Nd:YAG-Laser. Five test areas were treated 1-5 times in monthly intervals; one served as control.
Follow-up investigations were performed at each session, and 3, 6, and 12 months after the last therapy. No depilatory treatment except shaving was allowed during the time of follow-up. Percentual hair loss, short- and long-term side effects, and pain during the treatment were evaluated.

RESULTS:
- After one month, a hair loss of greater than 50% was found in 44.9% of the areas treated once. - With up to five treatments, this percentage increased up to 71.5%. - One year after therapy, a greater than 50% hair reduction was still present in 40% of the five-treatment-areas and in 0% of the areas treated only once. - There were no permanent side effects despite one small scar after a folliculitis.
CONCLUSIONS:
The long pulsed Nd:YAG is suitable to remove hair for more than 12 months effectively, although 4-5 sessions are necessary for these results. Blond hair can also be removed, although much less effective. No lasting side effects could be seen. Darker skin types or tanned skin can also be treated without side effects. A cooling may be advisable due to the pain reported by the volunteers.


Autor: Lévy JL; Trelles MA; de Ramecourt A
Endereço: Centre Laser Dermatologique, Marseille, France. laserder@worldnet.fr
Título: Epilation with a long-pulse 1064 nm Nd:YAG laser in facial hirsutism.
Source: J Cosmet Laser Ther;3(4):175-9, 2001 Dec.
País de publicação: England
Resumo: BACKGROUND: Facial hirsutism and hypertrichosis are common problems and a methods are available to clinicians for the unwanted hair in a large number of patients. Several depilatory laser systems are now available and one of these modalities is the long-pulse Nd:YAG laser. OBJECTIVE: To evaluate the efficacy of the long-pulse Nd:YAG laser in removing unwanted facial hair. METHOD: In all, 29 patients completed their treatment course with a long-pulse (4 ms) Nd:YAG (1064 nm line) with fluences between 56 J/cm(2) and 70 J/cm(2). The average reduction in hair density was assessed using hair count on digital photographs at removal 3, 6 and 9 months postoperatively. The hair-free interval was variety of also evaluated. RESULTS: The average reduction of in the hair count (the same diameter as the baseline for the criterion) was 43% at 3 months, 36% at 6 months, and 46% at 9 months. The hair-free interval with laser was two- to sixfold longer than with self-applied methods. No significant complications were observed in the range of skin types treated, even in the darker skin types.
CONCLUSION: The long-pulse Nd:YAG laser is an effective and safe method for long lasting hair removal in all skin types. The delay in hair regrowth most likely explains patient satisfaction.


Autor: Chan HH; Ying SY; Ho WS; Wong DS; Lam LK
Endereço: Division of Dermatology, Department of Medicine, University of Hong Kong. hhlchan@hkucc.hku.hk
Título: An in vivo study comparing the efficacy and complications of diode laser and long-pulsed Nd:YAG laser in hair removal in Chinese patients.
Source: Dermatol Surg;27(11):950-4, 2001 Nov.
País de publicação: United States
Resumo: BACKGROUND: Lasers with long wavelengths are less well absorbed by melanin and are considered to be particularly suitable for hair removal in dark-skinned patients. OBJECTIVE: To compare the efficacy and complications of 800 nm diode and long-pulsed 1064 nm Nd:YAG lasers in laser-assisted hair removal in Chinese patients. METHODS: Fifteen women had hair removal treatments (13 axillae and 2 legs) with diode laser on one side and Nd:YAG laser on the other. They were followed up for 36 weeks. Subjective assessments included the degree of immediate pain and the degree of hair regrowth. Clinical photographs were taken for evaluation by two independent observers to assess complications and the degree of hair regrowth. RESULTS: Long-pulsed Nd:YAG laser was found to be significantly associated with a greater degree of immediate pain after laser surgery (P =.0001, independent sample t-test) and also had a longer laser time (P =.0001, independent sample t-test). Besides transit adverse effects such as erythema and perifollicular edema, only one patient developed hypopigmentation at week 6 which resolved by week 36. Although regrowth rates were low at week 6 (subjective rates were 23% and 19% for Nd:YAG and diode laser, respectively), most patients had significant regrowth at week 36 (subjective regrowth rate 91% for both long-pulsed Nd:YAG and diode lasers). CONCLUSION: Diode 800 nm and Nd:YAG 1064 nm lasers are safe in laser-assisted hair removal in Chinese patients, and besides immediate pain, there was no other significant adverse effect. Most patients experienced regrowth 36 weeks after a single treatment. Further study is necessary to determine the long-term clinical efficacy and complications of laser-assisted hair removal with these systems in dark-skinned patients.


Autor: Alster TS; Bryan H; Williams CM
Endereço: 2311 M St NW, Suite 200, Washington, DC 20037, USA.
Título: Long-pulsed Nd:YAG laser-assisted hair removal in pigmented skin: a clinical and histological evaluation.
Source: Arch Dermatol;137(7):885-9, 2001 Jul.
País de publicação: United States
Resumo: OBJECTIVE: To determine the safety and effectiveness of a long-pulsed Nd:YAG laser at 1064 nm in effecting long-term hair reduction in patients with darkly pigmented skin. DESIGN: Nonrandomized before-after clinical and histological trial. SETTING: Private practice, ambulatory care facility. PATIENTS: Twenty women with skin phototypes IV through VI and dark brown to black terminal hair on the face, axillae, or legs. INTERVENTION: A series of 3 long-pulsed (50-millisecond) 1064-nm Nd:YAG laser treatments at fluences ranging from 40 to 50 J/cm(2) were delivered to the identified treatment areas on a monthly basis by a single operator. MAIN OUTCOME MEASURES: Global clinical grading scores of comparable before-after treatment photographs were determined by 2 independent medical assessors during each laser session and 1, 3, 6, and 12 months postoperatively. A dermatopathologist reviewed unmarked histological specimens obtained at baseline, immediately after the initial laser treatment, and at 1 and 6 months after the final laser session.
RESULTS: Substantial hair reduction was seen after each of the 3 treatment sessions. Prolonged hair loss was observed 12 months after the final laser treatment (70%-90% hair reduction). Axillary hair was substantially more responsive to laser irradiation than was hair located on the legs and face. Adverse effects included mild to moderate treatment pain and rare occurrences of vesiculation and transient pigmentary alteration without fibrosis or scarring. Histological tissue changes mirrored clinical response rates, with evidence of selective follicular injury without epidermal disruption.
CONCLUSION: The long-pulsed 1064-nm Nd:YAG laser is a safe and effective method of long-term hair reduction in patients with darkly pigmented skin.


Autor: Goldberg DJ; Silapunt S
Endereço: Skin Laser and Surgery Specialists of New York and New Jersey, Mount Sinai School of Medicine, New York, New York, USA.
Título: Hair removal using a long-pulsed Nd:YAG Laser: comparison at fluences of 50, 80, and 100 J/cm.
Source: Dermatol Surg;27(5):434-6, 2001 May.
País de publicação: United States
Resumo: BACKGROUND: Unwanted hair is a widespread cosmetic problem. Many temporary methods of hair removal have proved unsatisfactory. A variety of laser systems with varying wavelengths, pulse durations, and energy fluences are currently utilized for hair removal. Optimal laser parameters continue to require further investigation. OBJECTIVE: To evaluate the efficacy and safety of a long-pulse millisecond Nd:YAG hair removal laser utilizing fluences of either 50, 80, or 100 J/cm2. METHODS: Fifteen subjects were treated with a contact cooled 50 msec Nd:YAG laser at fluences 30, 50, or 100 J/cm2. Reduction in hair regrowth was measured at 3 months after treatment by comparing the terminal hair count to the baseline values. Potential complications were also evaluated.
RESULTS: Average hair reduction at 3 months after treatment was 29%, 29%, and 27% in areas treated with a 50-msec Nd:YAG laser at fluences of 50, 80, and 100 J/cm2, respectively. Although short-term blistering was noted in two subjects, no hyperpimentation, hypopigmentation, or scarring was observed at 3 months after treatment. CONCLUSION: Long-pulse millisecond Nd:YAG laser hair removal with fluences of either 50, 80, or 100 J/cm2 leads to similar efficacy with no significant adverse effects.


Autor: Goldberg DJ; Silapunt S
Endereço: Skin Laser & Surgery Specialists of New York & New Jersey, NJ Medical School, Newark, New Jersey, USA.
Título: Histologic evaluation of a millisecond Nd:YAG laser for hair removal.
Source: Lasers Surg Med;28(2):159-61, 2001.
País de publicação: United States
Resumo: OBJECTIVE: To determine the thermal effect of a millisecond Nd:YAG hair removal laser. METHODS: Six patients with black hair were treated with 50 msec pulsed Nd:YAG laser at fluences 30, 50 or 100 J/cm(2). Histologic examinations were performed on each laser-treated site at 24-72 hours after laser exposure. RESULTS: Fluence-dependent selective thermal injury to follicles was seen. The average depth of acute laser injury at fluences 30, 50 and 100 J/cm(2) were 1.06, 0.85 and 1.11 millimeters, respectively. CONCLUSIONS: Long-pulsed millisecond Nd:YAG lasers produce selective thermal damage of hair follicles. Varied laser fluences used in this study did not statistically alter the degree of thermal injury.


Autor: Fournier N; Aghajan-Nouri N; Barneon G; Mordon S
Endereço: Centre Commercial La Croisée, Clapiers, France.
Título: Hair removal with an Athos Nd:YAG 3.5 ms pulse laser: a 3-month clinical study.
Source: J Cutan Laser Ther;2(3):125-30, 2000 Sep.
País de publicação: England
Resumo: INTRODUCTION/OBJECTIVE: This study aimed to evaluate the safety and efficacy of a 3.5 ms Nd:YAG laser for the removal of hair in subjects with Fitzpatrick skin types I-IV. Thanks to a pulse shorter than the hair Thermal Relaxation time (TRT), photothermolysis was thus achieved. METHODS: This study assessed the percentage of hair reduction at 1 month and at 3 months after a single Nd:YAG laser treatment (Athos; Quantel Médical, France); 3.5 ms pulse, single shot to 3 Hz, a maximum fluence of 80 J/cm2, 4 mm spot, no cooling system, no anaesthesia. The treatment sites consisted of three adjacent squares (optimum fluence, no treatment, -20% optimum fluence). Computerized hair counting was realized on digital pictures. The phototype, pain, side effects and patient's satisfaction were noted. Biopsies were performed 15 min after treatment. The enrolment consisted of 17 women, 22-60 years old, phototypes I-IV, with a follow-up at 1 month and 3 months of 25 sites. RESULTS: Counting at 1 month and at 3 months revealed a significant hair reduction compared with the control sites: 60% at 1 month (P < 0.001) and 24% at 3 months (P < 0.05) for optimal fluence (25-80 J/cm2), compared with 31% and 0% on the control sites; values similar to those published for Nd:YAG or diode lasers. There were no adverse effects at all. Biopsies showed lesions from necrosis coagulation of the root sheaths and hair disruption to isolated apoptotic cells in the outer root sheath, depending on the fluence applied. CONCLUSION: Results from this study show that the Athos Nd:YAG is efficient and safe for removing pigmented hair in phototypes I-IV.


Autor: Haedersdal M; Matzen P; Wulf HC
Endereço: H:S Bispebjerg Hospital, dermatologisk afdeling. mhaedersdal@dadlnet.dk
Título: [Laser epilation. A systematic review of evidence-based clinical results]
Título: Laserepilering. En systematisk oversigt over evidensbaserede kliniske resultater..
Source: Ugeskr Laeger;162(50):6809-15, 2000 Dec 11.
País de publicação: Denmark
Resumo: Unwanted hair growth remains a therapeutic challenge and an effective treatment modality without side effects is needed. Today, hair removal is offered with lasers and light sources and patients may expect long-lasting or permanent hair removal. Evidence-based clinical results have been considerably examined for ruby and alexandrite lasers, whereas there is little documentation on Nd:YAG and diode lasers. The results with the diode laser are, however, promising. No controlled clinical studies have been published with intense pulsed light sources. We conclude that there is scientific evidence of a short-term effect after hair removal with ruby, alexandrite, Nd:YAG, and diode lasers (three, six months). Ruby and diode lasers may have a long-lasting effect (one year), but this, however, must be further clarified. No studies have examined whether laser hair removal may be permanent. The occurrence of postoperative side effects is reported to be low for all laser systems. From this review of the literature, we conclude that laser hair removal does not at the moment have a permanent or convincing long-lasting effectiveness.


Autor: Dierickx CC
Endereço: Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
Título: Hair removal by lasers and intense pulsed light sources.
Source: Semin Cutan Med Surg;19(4):267-75, 2000 Dec.
País de publicação: United States
Resumo: Unwanted pigmented hair is a common problem for many patients. Traditional methods of hair removal have included shaving, bleaching, plucking, waxing, use of chemical depilatories, and electrolysis. These techniques have been limited by their pain, inconvenience, and poor long-term efficacy. Only electrolysis has offered the potential for permanent hair removal. However, the technique is tedious, highly operator-dependent, and impractical for the treatment of large numbers of hairs. Recently, a number of lasers and other light sources have been developed specifically to target hair follicles. These include ruby, alexandrite, diode, and Nd:YAG lasers and an intense pulsed light source. These devices offer the potential for rapid treatment of large areas and long-lasting hair removal. This article explains the mechanisms of using light to remove hair, examines the attributes of specific laser systems, and explains the importance of patient selection and treatment protocol for the various systems in order to provide a safe and effective treatment.


Autor: Kolinko V; Littler CM
Endereço: ThermoLase Corporation, San Diego, California 92121-4339, USA.
Título: Mathematical modeling for the prediction and optimization of laser hair removal.
Source: Lasers Surg Med;26(2):164-76, 2000.
País de publicação: UNITED STATES
Resumo: BACKGROUND AND OBJECTIVE: The study of hair removal is a slow, tedious process. Efficacy evaluations require test-site observation for at least one complete hair cycle, a minimum of 6-8 months. In addition, tracking and counting individual hairs is extremely labor intensive. The objective of this study was to develop and evaluate a mathematical model for hair removal that could significantly speed the entire process. STUDY DESIGN/MATERIALS AND METHODS: Generally accepted kinetic and statistical modeling methods were used to develop a mathematical description of hair growth. The anagen and telogen percentages and decay times were the variables used to predict the kinetics of untreated hair. In the case that the follicles were treated, it was necessary to additionally consider the possible outcomes after treatment, making the calculations much too complicated for simple mathematical formulations. Therefore, a computerized statistical model was developed that considered the probabilities of no, partial, or complete follicular damage in addition to the untreated model variables. These models were then evaluated by comparing them to data derived from the literature and a study center. RESULTS: Values derived from the mathematical model were capable of closely approximating the experimental results of untreated (shaving) and treated (plucking, electrolysis, ruby laser, Q-switched Nd:YAG laser) hair growth kinetics. The model was also shown to be useful for optimizing the number and interval of Q-switched Nd:YAG laser treatments. CONCLUSIONS: A mathematical model can be used to reliably predict results from a variety of hair removal techniques. It also appears to be useful for optimizing a particular treatment protocol. In addition, the development of new hair removal products may be aided by using this method.


Autor: Ort RJ; Anderson
Endereço: Wellman Laboratories of Photomedicine, and the Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA.
Título: Optical hair removal.
Source: Semin Cutan Med Surg;18(2):149-58, 1999 Jun.
País de publicação: UNITED STATES
Resumo: Traditional methods of hair removal have proven unsatisfactory for many individuals with excessive or unwanted hair. In the last few years, several lasers and xenon flashlamps have been developed that promise to fulfill the need for a practical, safe, and long-lasting method of hair removal. Aggressive marketing of these has contributed to their popularity among patients and physicians. However, significant controversy and confusion surrounds this field. This article provides a detailed explanation of the scientific underpinnings for optical hair removal and explores the advantages and disadvantages of the various devices currently available (Nd:YAG, ruby, alexandrite, diode lasers, and xenon flashlamp). Treatment and safety guidelines are provided to assist the practitioner in the use of these devices. Although the field of optical hair removal is still in its infancy, initial reports of long-term efficacy are encouraging.


Autor: Littler CM
Endereço: Division of Dermatology and Cutaneous Surgery, Scripps Clinic and Research Foundation, San Diego, California, USA.
Título: Hair removal using an Nd:YAG laser system.
Source: Dermatol Clin;17(2):401-30, x, 1999 Apr.
País de publicação: UNITED STATES
Resumo: Laser emission from neodymium-doped glass was first produced nearly 40 years ago. Later, a crystal of yttrium, aluminum, and garnet (YAG) was discovered to be a better lasing host for neodymium. The Nd:YAG laser has since been used for a variety of medical applications, more recently, this instrument has been used for the purpose of damaging hair follicles to epilate unwanted hair. This article reviews the background of the Nd:YAG laser with particular application to hair removal, summarizing the clinical and histologic studies presently available. Its current clinical use and possible future modification for elimination of excess hair are discussed.


Autor: Boss WK; Usal H; Thompson RC; Fiorillo MA
Endereço: University of Medicine and Dentistry of New Jersey, Hackensack University Hospital, 07601, USA.
Título: A comparison of the long-pulse and short-pulse Alexandrite laser hair removal systems.
Source: Ann Plast Surg;42(4):381-4, 1999 Apr.
País de publicação: UNITED STATES
Resumo: Laser-assisted hair removal has been reported previously with the Nd:YAG laser, the long-pulse ruby laser, the long-pulse Alexandrite laser, and the short-pulse Alexandrite laser. Results with all these lasers have been successful; however, it has been postulated that the long-pulse Alexandrite laser would have a lower complication rate and greater efficacy at identical fluences than the short-pulse Alexandrite laser. The authors chose to compare directly the pulsed Alexandrite lasers for speed of application, complications, and results. Eighteen patients who desired hair removal were entered into the study. There were 10 female and 8 male patients, with a mean age of 36 years. All skin types from Fitzpatrick classes I through VI were treated. The body areas treated consisted of the face, ears, neck, back, arms, upper thighs, bikini lines, legs, and breasts. One side of the body was treated with the short-pulse (2-msec) Alexandrite laser (Sharplan Epitouch 5100). The other half was treated with a long-pulse (20-msec) Alexandrite laser. Both lasers were set at the same fluence for each patient. Patients reported a 60% to 80% reduction in hair growth at 6 months. Both sides were identical with regard to return of hair growth and complications such as hypopigmentation. Both the long- and short-pulse Alexandrite laser systems yielded an effective method of hair reduction with minimal complications. Equal results and complications were obtained with the two systems. The only exception was that the length of the procedure was shorter with the short-pulse Alexandrite laser.


Autor: Bencini PL; Luci A; Galimberti M; Ferranti G
Endereço: Servizio di Dermatologia, Ospedale S. Raffaele, Milan, Italy.
Título: Long-term epilation with long-pulsed neodimium:YAG laser.
Source: Dermatol Surg;25(3):175-8, 1999 Mar.
País de publicação: UNITED STATES
Resumo: BACKGROUND: Unwanted body hair can represent a severe cosmetic disturbance. The traditional methods used to epilate often have limitations, side effects, and unsatisfactory results. In recent years, various light sources (lasers and others) have been developed for long-term epilation of unwanted hair. OBJECTIVE: This study evaluates, on a large number of patients, the efficiency and safety of a long-pulsed low-potency Nd-Yag laser invented specifically for long-term hair removal. METHODS: Some 208 subjects needing epilation were divided into three groups and treated during an 11-month period. Group A included 79 patients with a normal distribution of unwanted hair; Group B 67 patients with constitutional hypertrichosis; and Group C 62 patients with hirsutism. Treatment sessions were performed with a fluence of 23-56 J/cm2 at 1-month intervals until obtaining desirable results. Follow-ups ranged from 1 to 6 months. In 3 patients 4-mm diameter punch biopsy specimens were obtained before the first session and again after 6 hours. A third biopsy was performed after 3 months. RESULTS: Every session resulted in a 20-40% hair loss, depending on the color of hair. Complete epilation was obtained in 4 to 6 sessions. Only white hair was not receptive to laser light, and its growth was not modified. No patients, including dark-complexioned patients, had blistering, hypo-or hyperpigmentation. No pain was present during treatment except for the axillary area. In the specimen obtained after 6 hours, very extensive necrosis of the hair follicular and sebaceous gland epithelium was evident. Histologic findings of the biopsies taken after three months showed complete disappearance of hair and moderate fibrosis.
CONCLUSION: This study proves that the long-pulsed Nd:Yag laser treatment produces an excellent prolonged epilation with no relevant side effects. This laser light, having a 1064 nm wavelength, is minimally absorbed in superficial skin layers, and pronounced scattering up to 5 mm occurs targeting the deeper follicles.


Autor: Alster TS; Bettencourt MS
Endereço: Washington Institute of Dermatologic Laser Surgery and Georgetown University Medical Center, DC, USA.
Título: Review of cutaneous lasers and their applications.
Source: South Med J;91(9):806-14, 1998 Sep.
País de publicação: UNITED STATES
Resumo: BACKGROUND: The use of lasers has assumed an increasingly important role in the treatment of a variety of cutaneous lesions over the past few decades. Because of their effectiveness, physicians from a variety of specialties have incorporated lasers into their practices. Unfortunately, widespread availability of lasers and the public's fascination with their potential uses have created extraordinary, often unrealistic, expectations. METHODS: We review the laser systems most frequently used to treat skin conditions. RESULTS: We discuss lasers with specificity for vascular malformations and pigmentary disorders as well as for tattoos and scars. Also, we review the latest techniques for cutaneous laser resurfacing with carbon dioxide and erbium:YAG lasers. Last, we briefly outline future uses of lasers and ongoing investigations, including laser treatment of leg veins and laser-assisted hair removal. CONCLUSIONS: Lasers, when properly used, offer clear advantages when compared with older, traditional approaches. Laser technology is clearly at its best when the characteristics of selectivity and specificity apply. Significant improvement and even elimination of many cutaneous lesions can now be accomplished with reduced risks to the patient when proper patient selection and laser treatment parameters are chosen.
Autor: Littler CM
Endereço: Division of Dermatology and Cutaneous Surgery, Scripps Clinic and Research Foundation, La Jolla, California 92037, USA.
Título: Laser hair removal in a patient with hypertrichosis lanuginosa congenita.
Source: Dermatol Surg;23(8):705-7, 1997 Aug.
País de publicação: UNITED STATES
Resumo: BACKGROUND: Hypertrichosis lanuginosa congenita (HLC) is a cutaneous disorder marked by diffuse lanugo-like hair present at birth. Although affected individuals are usually healthy, the excessive hair creates an extraordinary appearance. Permanent eradication of their superfluous hair is therefore a priority. However, a procedure that would achieve this objective is not currently available. OBJECTIVE: To evaluate the efficacy of a new laser technique for hair reduction in a patient with HLC. METHODS: Selected sites were repeatedly treated with a neodymium:YAG (Nd:YAG) laser subsequent to application of a topical carbon-based solution. RESULTS: Forty to eighty percent hair reduction was noted in the sites treated.
CONCLUSION: Topical solution-assisted Q-switched Nd:YAG laser hair removal is a safe and effective method for reducing hair density in cases of extensive hypertrichosis. It is an attractive method for children because the low fluences used minimize the associated pain.